Latest Episode
What Should We Eat? Evolution, Diet, and Eating Well with Daniel Lieberman
What did humans actually evolve to eat? With paleo, keto, vegan, Mediterranean, and a thousand other diets all claiming to be "the one," it's no wonder people feel whiplashed every time they walk into a grocery store. But what if the answer isn't found in the latest diet book, but in millions of years of human evolution?
Join Holly and Jim as they welcome back Harvard evolutionary biologist Dan Lieberman for a second appearance on the show. This time, Dan isn't talking exercise. He's talking fo
Recent Episodes
143
Sept. 9, 2026
What Should We Eat? Evolution, Diet, and Eating Well with Daniel Lieberman
What did humans actually evolve to eat? With paleo, keto, vegan, Mediterranean, and a thousand other diets all claiming to be "the one," it's no wonder people feel whiplashed every time they walk into a grocery store. But what if the answer isn't found in the latest diet book, but in millions of years of human evolution? Join Holly and Jim as they welcome back Harvard evolutionary biologist Dan Lieberman for a second appearance on the show. This time, Dan isn't talking exercise. He's talking fo
142
Sept. 2, 2026
Ten Key Decisions That Shape Your Weight Loss Success
Most people trying to lose weight obsess over the what: what diet, what medication, what workout plan. But according to Holly and Jim, the real key to long-term success isn't found in any of those choices. It's found in a set of decisions most people never even realize they're making. In this episode, Holly and Jim count down the 10 decisions that determine whether a weight loss journey actually sticks. Some are questions you'd expect. Others might catch you completely off guard, including the
141
Aug. 26, 2026
Triple Agonists: Revolutionizing Weight Loss or Too Much of a Good Thing?
For years, the ceiling on medical weight loss was 15%, maybe 20% if you were lucky. Now a new triple-target medication is posting average results that flirt with 30% body weight loss in clinical trials, numbers once reserved for the operating room. Holly and Jim sat down to unpack what's driving these results, and found themselves asking a question neither expected to ask in their careers: how much weight loss is actually too much? Retatrutide, the drug at the center of this episode, adds a thi
140
Aug. 19, 2026
The Power of Mindfulness for Eating Habits and Weight Management
Can simply paying attention to your first bite of food change how much you eat? It sounds too simple to matter, but Holly and Jim are digging into a topic that might seem completely outside their lane: mindfulness and meditation. For years, mindfulness has been filed under "stress management," not "weight management." But a growing body of research is asking a bigger question: can training the mind actually change the way we eat, not by altering our biology, but by changing how we respond to it
139
Aug. 12, 2026
The Five Minute Prescription: Online GLP-1 Meds and the Future of Obesity Care
A few clicks online. No exam, no phone call, no video visit. Minutes later, a GLP-1 prescription is headed to your door. It sounds like the future of healthcare: fast, easy, convenient. But is convenience the same thing as care? A Yale research team wanted to find out, so they built a fake patient, sent her to 49 different online GLP-1 providers, and tracked exactly what happened. What they found may change the way you think about getting these medications online and raise questions you didn't
138
Aug. 5, 2026
The New Science of Food Noise and Its Impact on Weight Loss
For years, patients kept telling Holly the same strange thing: it wasn't the number on the scale that changed their life, it was something quieter, something they'd never had words for. They just didn't think about food anymore. Now that experience has a name, and for the first time, a way to measure it. Food noise has gone from an offhand comment on social media to one of the most talked-about concepts in obesity science, and Holly and Jim are back to unpack how far the research has come since
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