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The Science and Realities of Long-Term GLP-1 Use
Losing weight on a GLP-1 medication can feel like magic until the scale stops moving. For almost everyone on these drugs, there comes a moment when the rapid progress slows, then stalls completely. Is the medication failing? Has your metabolism adapted? Did you do something wrong? For most people, that moment feels like a problem. It isn't. Join Holly and Jim as they unpack one of the most misunderstood parts of the GLP-1 journey: the shift from losing weight to keeping it off. You'll discover w
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132
June 24, 2026
The Science and Realities of Long-Term GLP-1 Use
Losing weight on a GLP-1 medication can feel like magic until the scale stops moving. For almost everyone on these drugs, there comes a moment when the rapid progress slows, then stalls completely. Is the medication failing? Has your metabolism adapted? Did you do something wrong? For most people, that moment feels like a problem. It isn't. Join Holly and Jim as they unpack one of the most misunderstood parts of the GLP-1 journey: the shift from losing weight to keeping it off. You'll discover w
131
June 17, 2026
The Hidden Influence of Community and Environment with Christina Economos
What if the biggest obstacle to your health isn't your willpower, it's your zip code? Most of us have been raised to believe that weight and health come down to personal choices: what you eat, how much you move, how disciplined you are. But what if the deck has been stacked against millions of Americans before they ever make a single decision? This week, Holly and Jim sit down with Dr. Christina Economos, Dean of the Friedman School of Nutrition Sciences and Policy at Tufts University, to explor
130
June 10, 2026
The Rise and Fall of Popular Diets Over 100 Years
If you've spent years hopping from one diet to the next: low fat, then low carb, then keto, then intermittent fasting, you're not alone, and you're not failing. The truth is, the diet world has been cycling through the same promises, the same villains, and the same disappointments for nearly a hundred years. And most of us never stop to ask why. Join Holly and Jim as they do something they've never done before on the show: step back and take a decade-by-decade look at almost 100 years of dieting
129
June 3, 2026
Why Dietitians Matter More Than Ever with Maha Tahiri
Millions of people are now taking GLP-1 medications and losing weight, but is eating less the same as eating better? The answer, according to today's guest, is a resounding no. And almost nobody in medicine, food, or public health is talking seriously about what happens when appetite disappears, but nutritional needs don't. Join Holly and Jim as they sit down with Dr. Maha Tahiri, a nutrition scientist, food industry strategist, and founder of Nutrition Sustainability Strategies, for one of the
128
May 27, 2026
What Comes After GLP-1 Success with Ken Fujioka
What if the medications changing everything about obesity treatment are also creating problems nobody saw coming? We’re living through a genuine before-and-after moment in obesity medicine. Drugs that once seemed like science fiction are now producing 20, even 25% weight loss in real patients. But the questions piling up are just as staggering as the results: What happens to your muscle? Your bone? Your sense of self? And what happens when the medication stops? Holly and Jim sit down with Dr. Ke
127
May 20, 2026
What the Nutrition Guidelines Still Haven't Caught Up To with Arne Astrup
Everyone has been burned by nutrition advice that completely reversed itself a few years later. Eggs were dangerous, then essential. Butter was poison, then practically a health food. Fat was the enemy until we realized what replaced it might have been even worse. If you've ever thrown up your hands and wondered whether nutrition scientists agree on anything , you're not alone. What if the confusion isn't just about changing science but about how nutrition guidelines are made, who influences the
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